FRONTLINE Plus for Dogs has been trusted by veterinarians for flea and tick control for dogs for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene one to kill adult fleas and ticks and the second to kill flea eggs and larvae this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older, 23-44 lbs. Its long-lasting formula is stored in the oil glands of the pets skin to give non-stop flea and tick protection for a full 30 days. Directions for Use Step 1. To REMOVE Applicator: 1. Use scissors to separate one blister; 2. Use scissors to cut along dotted line; 3. Peel down foil to remove the applicator. Step 2. OPEN Applicator. Hold upright with foil side toward you and snap applicator tip. Step 3. APPLY FRONTLINE Plus. Part the dogs hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the dogs skin. Do not apply on top of the hair coat. Avoid contact with treated area until dry. Do not allow your dog to ingest the product. Do not apply to dogs weighing less than 23 lbs. or younger than 8 weeks of age. Do not use more than one application per dog per month. Frequency Use monthly to control fleas and ticks. Do not reapply FRONTLINE Plus for 30 days.